Ireland will face Wales this Sunday at the Principality Stadium in Cardiff in a massive game kicking off at 3pm. Both sides are coming in to this on a pretty much even footing and they will be both desperate to get off to a winning start. If you lose your first game, you are always up against in trying to win the tournament.
Here is the Irish team and the big call is Tadhg Beirne starting ahead of Iain Henderson and Tadhg Furlong is on the bench after being out injured for the best part of the year. See the team below.
England also take on Scotland on Saturday at Twickenham and France take on Italy, in the opening weekend of the Six Nations, a rugby feast for rugby fans. A great weekend all round for sports fans with Liverpool vs Manchester City on Sunday also, another cracker to look forward to.